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The ESR integration in the planned research will be accomplished by collegiate scientific direction, training events and courses of transferable skills, and secondments to basic and applied research institutes and private enterprises. Figure 3. The first research work package comprises laboratory work WP3 , which includes single cell sorting, nucleic acid amplification from the minute quantities in a single cell, and highthroughput sequencing.

The second is bioinformatics WP4 , by which the billions of short sequences are processed into comprehensive datasets, requiring assembly into larger contigs, gene prediction and annotation, and reconstruction of metabolic pathways. The generated genomic data is then exploited to address scientific questions within two tightly interconnected disciplines, which if tackled separately could not be answered.

Fundamental ecological questions WP5 include the study of the biodiversity of natural samples, cell-to-cell interactions, and gene complements of uncultured lineages that could explain their lifestyle and ecological function. Evolutionary questions WP6 include the addition of uncultured lineages to retrieve a more complete eukaryotic Tree of Life, understanding the evolution of genes and pathways across different lineages, and population genomics in a given lineage or species group. This project has received funding from the European Union's horizon research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No Project overview.

Figure 2. Overview of the steps involved in Single Cell Genomics. How does the uncultured diversity populate the eukaryotic tree of life, including novel branches and deep evolutionary events? Can genetic repertoires explain the success of certain uncultured lineages in natural environments? Can genomic data explain the functional diversity of related lineages occupying similar ecological fields? What is the distribution in the ocean of species and functions, and what are their drivers? SCG allows a view of the genome variability within a microbial population.

Eukaryote microbial genomics

This is used in biomedicine to understand cancer origins and development and can also be applied in classical population genetics that aims to describe genetic variation accumulation within populations prior to diversification, or to understand how microbial cells interact and cooperate to perform key ecological functions. We also will look into how protists interact with the environment and manage to be biological success.

Within the six modules, we will speak of 1 what protists are, 2 flagellates, 3 sarcodines and slime molds, 4 ciliates, 5 apicomplexans and microsporidians, and 6 finally we will go over the modern phylogeny, will summarize life histories and discuss evolutionary trends in free-living and parasitic protists.

This online course will have an optional on-campus extension, when the students have one week of practical exercises in the lab. Using light microscopy, they will observe, explore, and document live specimens and fixed mounts of naked and testate amoebas, foraminiferans, radiolarians, heliozoans, myxomycetes, flagellates, ciliates, gregarines, and coccidians. Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free. More questions?

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Prokaryotic vs. eukaryotic genomes

Basic Science. Protists: Evolution and Ecology of Microbial Eukaryotes. Offered By. Saint Petersburg State University. About this Course 2, recent views. Flexible deadlines. Flexible deadlines Reset deadlines in accordance to your schedule.

Researchers Rethink the Ancestry of Complex Cells

Intermediate Level. Hours to complete. Available languages. English Subtitles: English.

Genome-reconstruction for eukaryotes from complex natural microbial communities

Chevron Left. Syllabus - What you will learn from this course. Video 6 videos. Reading 4 readings.

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Supplementary materials: Definition 10m. Supplementary materials: Cell Biology 10m. Supplementary materials: Phylogenetic tree 10m. Supplementary materials: Ecology of protists 10m. Quiz 5 practice exercises. Quiz 6m. Quiz 2m. Quiz 4m. Control test 15m. Video 5 videos. Mineral skeleton 4m. Reading 3 readings. Supplementary materials 10m. Supplementary materials: Protistan skeletons 10m. Supplementary materials: Pseudopodia 10m. Quiz 6 practice exercises.